Search on: FACTOR VIIIA 
Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   Factor VIIIa 
Descriptor Spanish:   Factor VIIIa 
Descriptor Portuguese:   Fator VIIIa 
Synonyms English:   Blood Coagulation Factor VIII, Activated
Factor VIIIa Heavy Chain, 200 kDa Isoform
Factor VIIIa Heavy Chain, 92 kDa Isoform
Factor VIIIa Light Chain
Activated Factor VIII
Factor VIII, Thrombin Activated
Factor VIIIa, Coagulation
Thrombin-Activated Factor VIII
VIIIa, Coagulation Factor
Factor VIII, Activated
Factor VIII, Thrombin-Activated
Coagulation Factor VIIIa  
Tree Number:   D12.776.124.125.350.300
D23.119.350.300
Definition English:   Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similar in structure and generation to factor Va. 
Entry Combination - descr/qualif English:   Factor VIIIa/deficiency use Hemophilia A
 
See Related English:   Coagulants
 
History Note English:   90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   24644 
Unique Identifier:   D015944 

Occurrence in VHL: 		 

Similar:
  
DeCS CID-10 SciELO LILACS LIS